This medication is indicated for the short-term treatment of moderate to severe melasma of the face (darkening of the skin on the face, especially on the cheeks and forehead).

Vitacid Plus cream works by lightening the dark spots of melasma. Improvement occurs gradually over the course of treatment, and the first results usually appear after 4 weeks of treatment.

Do not use the product if you are allergic to the drug or its components. This medication is contraindicated for anyone under 18 years of age.

This medication should not be used by pregnant, suspected or breastfeeding women without medical advice.

Vitacid Plus before and after

Vitacid Plus before and after
Vitacid Plus before and after

Wash your face with a mild sanitizer (do not use a sponge). Rinse and dry the skin. apply Vitacid Plus cream at night, at least 30 minutes before bedtime.


Put a small amount (approximately the size of a pea) of Vitacid Plus at your fingertips. Apply a thin layer to cover the blemishes and another 0,5 centimeter of normal skin around the blemish.

After some time of treatment, you may notice that you will need to apply a slightly smaller amount of medication.

Vitacid Plus cream works by lightening the dark spots of melasma. Improvement occurs gradually over the course of treatment, and the first results usually appear after 4 weeks of treatment.

  • Spread the cream gently and evenly. The cream should “disappear” into the skin almost immediately. If it doesn't, it means you applied too much product.
  • Do not apply to the corners of the nose, mouth, eyes or on broken skin.
  • Spread the product always avoiding these areas.
  • If the skin becomes very irritated, stop using the product and consult a doctor.
  • To help prevent dryness, moisturizer can be used in the morning after washing your face.
  • Cosmetics can be used during the day as long as they are not comedogenic or irritating.
  • After finishing the treatment with Vitacid Plus cream, continue to protect your skin from the sun.

If the melasma reappears, the treatment can be restarted, until the lightening of the spots occurs again. The product has been shown to be safe for intermittent (non-continuous) use for up to 6 months.

In case of accidental ingestion, it is recommended to consult a doctor.


Follow your doctor's advice, always respecting the times, doses and duration of treatment. Do not stop treatment without your doctor's knowledge.

What should I do when I forget to use Vitacid Plus?

If you forget to apply the product, re-apply it normally the next night, no extra application is necessary.

If in doubt, seek advice from your pharmacist or doctor.

What precautions should I take when using Vitacid Plus?

Avoid overexposure to natural or artificial sunlight, as the stains can get even darker. Use sunscreen with a factor of 30 (minimum) and protective clothing, including a hat, when leaving the house.

If you have a sunburn, stop using Vitacid® Plus cream until your skin returns to normal.

Do not use the product in excess and do not apply more frequently than recommended by the doctor. It may irritate the skin and will not give you better or faster results.

Do not cover the area after applying Vitacid Plus cream.

Avoid products that can dry out or irritate the skin such as:

Soaps and cosmetics containing alcohol, fragrances or certain shampoos and hair perming products.

Attention: Do not use this medication without consulting your doctor if you are pregnant. It can cause problems for the fetus.

Tell your doctor if you are taking any other medicines.

Do not use medication without your doctor's knowledge. It can be dangerous for your health.

What are the adverse reactions and side effects of Vitacid Plus?

The following adverse reactions have been reported with the use of Vitacid Plus cream:

Mild to moderate redness, scaling, severe burning or swelling of the skin, dryness or itching (itching), severe or continued skin irritation, blistering, crusting, irritation of the eyes, nose and mouth, dark patches of skin (hyperpigmentation).

Stinging sensation, increased skin sensitivity, rashes, acne, skin redness, blisters, fine red lines or blood vessels visible through the skin (telangiectasia).

Some patients who are allergic to sulfites may experience severe allergic reactions to Vitacid Plus cream, with reactions including breathing problems or severe asthma attacks.

The following local adverse reactions have been reported infrequently with other topical corticosteroids, and may occur more frequently with the use of occlusive dressings, especially with higher potency corticosteroids.

In approximate order of decreasing occurrence:

Hypopigmentation (decreased production of skin pigments), perioral dermatitis (rash around the mouth), allergic contact dermatitis (allergy), secondary infection, stretch marks and miliaria (skin rash related to sweat glands).

Inform your doctor or pharmacist if you experience any undesirable reactions when using the medicine. Also inform the company through its customer service.

Overdose: What happens if I take a larger dose of Vitacid Plus than recommended?

Excessive use will not bring better or faster therapeutic results, and skin irritation may occur.

In case of using a large amount of this medicine, seek medical help quickly and take the medicine package or package insert, if possible. Call 0800 722 6001 if you need further advice.

Drug interaction: what are the effects of taking Vitacid Plus with other medicines?

Patients should avoid medicated or abrasive or drying soaps or sanitizers, products with a high concentration of alcohol and astringents, and other irritating or keratolytic medications.

During treatment with Fluocinolone Acetonide + Hydroquinone + Tretinoin. Patients should be advised to exercise caution with concomitant use of drugs known to be photosensitizing.